Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases
نویسندگان
چکیده
منابع مشابه
Emerging and re-emerging viral diseases: risks and controls
In the present globalized world with overflowing travels and trades, human health has been increasingly threatened due to incidences of emerging or/and re-emerging infectious diseases. The most important sources of novel human pathogens are mainly farm mammals and poultry, and to some extent, wild animals and arthropods. It is estimated that zoonosis constitute about 60% of the ‘known’, and up ...
متن کاملSynthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.
A convenient and versatile approach to the direct synthesis of a peptide-antigen matrix by the solid-phase method is described. The approach is called the multiple antigen peptide system (MAP) and it utilizes a simple scaffolding of a low number of sequential levels (n) of a trifunctional amino acid as the core matrix and 2n peptide antigens to form a macromolecule with a high density of peptid...
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The newest emerging viral infection of dogs is canine circovirus. It was thought to be the cause of illness and mortality in Ohio dogs in late August/early September 2013. Canine circovirus can either be the primary infection or present in the form of co-infection with other enteric pathogens. Its role as a primary pathogen still needs to be defined. In a recent paper, Linlin et al (1) document...
متن کاملEmerging and Re-emerging Viral Diseases of Large Animals
A single-nucleotide polymorphism (A(2254) or G(2254)) in the DNA polymerase gene of equine herpesvirus 1 (EHV-1) has been linked to the neuropathogenic phenotype which induces equine herpes myeloencephalitis (EHM). Based upon this, a real-time PCR assay to distinguish potentially neuropathogenic from non-neuropathogenic EHV-1 strains was described in 2007. With some limitations, this assay was ...
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ژورنال
عنوان ژورنال: Indian Journal of Virology
سال: 2013
ISSN: 0970-2822,0974-0120
DOI: 10.1007/s13337-013-0162-z